Description

2-Thiophenecarbonyl Chloride, 3-Methoxy-4,5-Dimethyl- (9Ci) is a specialized heterocyclic building block and acylating agent of significant interest in advanced organic synthesis. Its core value lies in its functionalized thiophene scaffold, which serves as a critical precursor for constructing complex molecules with tailored electronic and structural properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks.
• Ligand and Catalyst Development: Employed to synthesize sophisticated ligands for transition metal catalysis and organocatalysts.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry and method development.
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene ring contributes to color and stability properties.

Basic Information

Product Name	2-Thiophenecarbonyl Chloride, 3-Methoxy-4,5-Dimethyl- (9Ci)
CAS No.	133659-18-4
Molecular Formula	C8H9ClO2S
Molecular Weight	204.67 g/mol
Synonyms	3-Methoxy-4,5-dimethyl-2-thiophenecarbonyl chloride; 3-Methoxy-4,5-dimethylthiophene-2-carbonyl chloride; 4,5-Dimethyl-3-methoxythiophene-2-carbonyl chloride; 2-Thiophenecarbonyl chloride, 3-methoxy-4,5-dimethyl-; (3-Methoxy-4,5-dimethyl-2-thienyl)carbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonyl Chloride, 3-Methoxy-4,5-Dimethyl- (9Ci) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.