Description

1H-Pyrazole-5-Carbonyl Chloride, 3-Methyl-1-(1-Methylethyl)- (9Ci) is a specialized heterocyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its high reactivity, enabling efficient formation of amide and ester bonds to construct complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. Its unique pyrazole core offers a versatile scaffold for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the pyrazole moiety for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials due to its ability to introduce specific heterocyclic units.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Detail
Product Name	1H-Pyrazole-5-Carbonyl Chloride, 3-Methyl-1-(1-Methylethyl)- (9Ci)
CAS No.	133639-29-9
Molecular Formula	C8H11ClN2O
Molecular Weight	186.64 g/mol
Synonyms	3-Methyl-1-isopropyl-1H-pyrazole-5-carbonyl chloride; 1-Isopropyl-3-methyl-1H-pyrazole-5-carbonyl chloride; 1H-Pyrazole-5-carbonyl chloride, 3-methyl-1-(1-methylethyl)-; 3-Methyl-1-(propan-2-yl)-1H-pyrazole-5-carbonyl chloride; Isopropyl-methyl-pyrazole-5-carbonyl chloride; 5-Carbonyl chloride-3-methyl-1-isopropylpyrazole
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-5-Carbonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a quality management system and can support development projects requiring compliance with cGMP or other regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.