Description

5-Amino-3-Ribofuranosylpyrazolo(3,4-E)(1,3)Oxazine-7-One is a specialized nucleoside analogue with a complex heterocyclic structure. This compound is of significant interest for its role as a key intermediate in the synthesis of novel antiviral and anticancer agents, particularly within the field of nucleoside chemistry. It is primarily utilized by pharmaceutical R&D departments, fine chemical manufacturers, and academic research institutions focused on developing next-generation therapeutic compounds.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel nucleoside-based antiviral drugs.
• Anticancer Agent Research: Serves as a precursor in the development of experimental chemotherapeutic compounds targeting DNA/RNA synthesis.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and polymerase function.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for high-value, complex organic molecules.
• Academic & Institutional R&D: Fundamental research tool for studying structure-activity relationships (SAR) in modified nucleosides.

Basic Information

Product Name	5-Amino-3-Ribofuranosylpyrazolo(3,4-E)(1,3)Oxazine-7-One
CAS No.	133470-97-0
Molecular Formula	C10H11N5O6
Molecular Weight	297.23 g/mol
Synonyms	5-Amino-3-β-D-ribofuranosylpyrazolo[3,4-e][1,3]oxazine-7-one; 5-Amino-3-(β-D-ribofuranosyl)-7H-pyrazolo[3,4-e][1,3]oxazin-7-one; 3-β-D-Ribofuranosyl-5-amino-7H-pyrazolo[3,4-e][1,3]oxazin-7-one; 5-Amino-3-(β-D-ribofuranosyl)pyrazolo[3,4-e][1,3]oxazin-7-one; Nucleoside Oxazine Derivative; Pyrazolo-oxazine Nucleoside
EINECS	Contact for details

Quality Control

Our 5-Amino-3-Ribofuranosylpyrazolo(3,4-E)(1,3)Oxazine-7-One is manufactured under strict quality control protocols suitable for research and pharmaceutical intermediate applications. Each batch is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, and residual solvents are provided and available upon request. We adhere to cGMP principles where applicable to support our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C (refrigerated) or -20°C for extended periods.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.