Description

Oxetanocin Guanosine Triphosphate is a chemically modified nucleoside triphosphate analog, distinguished by its unique oxetane ring structure. This modification is critical for its role as a potent inhibitor of viral DNA polymerases, making it a valuable tool in antiviral research and drug discovery. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and academic institutions focused on virology and nucleotide biochemistry. The compound's specific mechanism of action provides a foundation for developing novel therapeutic agents.

Application

• Antiviral Research: Serves as a key biochemical tool for studying the inhibition mechanisms of viral polymerases, particularly for herpesviruses and hepatitis B virus.
• Nucleotide Analogue Synthesis: Acts as a sophisticated building block or precursor in the chemical synthesis of novel nucleoside and nucleotide analogs with therapeutic potential.
• Enzymology Studies: Used in in vitro assays to investigate substrate specificity and kinetics of DNA-dependent RNA polymerases and reverse transcriptases.
• Drug Discovery Pipeline: Employed in high-throughput screening (HTS) campaigns to identify and validate new leads for antiviral drug development.
• Biochemical Probe Development: Utilized to create labeled or tagged probes for studying nucleic acid metabolism and enzyme interactions within cellular systems.

Basic Information

Product Name	Oxetanocin Guanosine Triphosphate
CAS No.	133386-21-7
Molecular Formula	C14H19N6O15P3
Molecular Weight	628.25 g/mol
Synonyms	OXT-GTP; Oxetano-GTP; 9-[(2R,3R,4S)-3,4-Bis(hydroxymethyl)-2-oxetanyl]guanine triphosphate; Oxetanocin-G triphosphate; Acyclonucleoside triphosphate analog; Osetanocin guanosine 5'-triphosphate; Guanosine triphosphate oxetanocin analog
EINECS	Contact for details

Quality Control

Every batch of Oxetanocin Guanosine Triphosphate is manufactured and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.