Description

N(2)-(3,4-Dichlorobenzyl)Guanine is a high-purity, synthetic guanine derivative characterized by its specific substitution pattern. This compound serves as a critical pharmaceutical intermediate and research chemical in the development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers engaged in nucleoside analog synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of antiviral and anticancer nucleoside analogs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies related to purine metabolism.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, functionalized guanine derivatives with specialized properties.

Basic Information

Product Name	N(2)-(3,4-Dichlorobenzyl)Guanine
CAS No.	133338-58-6
Molecular Formula	C₁₂H₁₀Cl₂N₆O
Molecular Weight	325.15 g/mol
Synonyms	2-Amino-1,9-dihydro-9-oxo-6-[(3,4-dichlorophenyl)methyl]purine; 6-[(3,4-Dichlorophenyl)methyl]guanine; Guanine, N(2)-(3,4-dichlorobenzyl)-; 2-[(3,4-Dichlorobenzyl)amino]-1,9-dihydro-6H-purin-6-one; 6-(3,4-Dichlorobenzyl)guanine; N2-(3,4-Dichlorobenzyl)guanine
EINECS	Contact for details

Quality Control

Our N(2)-(3,4-Dichlorobenzyl)Guanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.