Description

Benzeneacetyl Bromide, α-Hydroxy- (9Ci) is a specialized organic bromide derivative characterized by its reactive acyl bromide and α-hydroxy functional groups. This compound is a valuable synthetic intermediate, enabling the efficient introduction of the phenylglyoxylic acid moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex active ingredients. Its precise reactivity profile makes it essential for constructing specific molecular architectures in advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring phenylglyoxylate or mandelate structures.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new organic transformations and novel compound libraries.
• Peptide Mimetics & Modifications: Employed to introduce specific side chains or protecting groups in the synthesis of peptide analogs and biomimetics.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal complexes.
• Fine Chemical Production: Intermediate in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name	Benzeneacetyl Bromide, α-Hydroxy- (9Ci)
CAS No.	133334-05-1
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	α-Hydroxybenzeneacetyl bromide; 2-Bromo-2-oxo-1-phenylethanol; Mandelic acid bromide; 2-Bromo-2-phenyl-2-oxoethanol; Phenylglyoxylic acid bromide; Hydroxy(phenyl)acetyl bromide; (RS)-Mandeloyl bromide; Bromo(phenyl)glyoxylic acid
EINECS	Contact for details

Quality Control

Our Benzeneacetyl Bromide, α-Hydroxy- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.