Description

(R)-Lanoconazole is the single enantiomer of the broad-spectrum antifungal agent Lanoconazole, distinguished by its specific stereochemistry. This high-purity chiral intermediate is critical for the development and manufacturing of advanced topical antifungal pharmaceuticals. It is essential for research institutions and pharmaceutical companies focused on enantioselective synthesis and the production of more potent, targeted therapeutic agents. The compound is supplied under stringent quality control to meet the exacting standards of the pharmaceutical industry.

Application

• As a key chiral building block in the synthesis of enantiomerically pure antifungal active pharmaceutical ingredients (APIs).
• For research and development of novel topical antifungal formulations with improved efficacy and safety profiles.
• In preclinical and clinical studies investigating the structure-activity relationship of imidazole antifungal agents.
• As a reference standard for analytical method development and quality control in pharmaceutical manufacturing.
• For use in asymmetric synthesis studies within academic and industrial organic chemistry laboratories.

Basic Information

Product Name	(R)-Lanoconazole
CAS No.	133267-38-6
Molecular Formula	C14H7Cl2N3S2
Molecular Weight	352.26 g/mol
Synonyms	(R)-N-[4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene]-1H-imidazol-1-amine; (R)-N-[(4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene)]-1H-imidazol-1-amine; (R)-Lanoconazole; (R)-Astat; (R)-NND-318; (R)-Dermaleve; (R)-Enantiomer of Lanoconazole
EINECS	Contact for details

Quality Control

Our (R)-Lanoconazole is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as chiral purity, enantiomeric excess (ee), and related substances. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with client requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.