Description

Benzenepropanoyl Chloride, 4-Fluoro- is a versatile fluorinated aromatic acid chloride intermediate. This compound is valued for its reactivity as an acylating agent, enabling the efficient introduction of the 4-fluorohydrocinnamoyl moiety into target molecules. It is primarily utilized by research and development chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and stability.
• Peptide Chemistry: Serves as an acylating agent for the modification of amino acids or peptides to create specialized derivatives.
• Material Science Research: Employed in the development of specialty polymers and liquid crystals, contributing to unique material properties.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in proteomics and diagnostic assay development.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to global clients.

Basic Information

Product Name	Benzenepropanoyl Chloride, 4-Fluoro-
CAS No.	133188-66-6
Molecular Formula	C9H8ClFO
Molecular Weight	186.61 g/mol
Synonyms	4-Fluorohydrocinnamoyl Chloride; 3-(4-Fluorophenyl)propionyl Chloride; 4-Fluoro-β-phenylpropionyl Chloride; 3-(4-Fluorophenyl)propanoyl Chloride; (4-Fluorophenyl)propanoic Acid Chloride; 4-Fluorobenzene propanoic acid chloride; 4-Fluoro-benzenepropanoyl chloride
EINECS	Contact for details

Quality Control

Our Benzenepropanoyl Chloride, 4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your project specifications and support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.