Description

Benzo[C]Thiophene-1-Carbonyl Chloride (9Ci) CAS NO 133179-63-2 is a high-purity, reactive organic intermediate characterized by its acid chloride functional group fused to a benzothiophene core. This compound is a critical building block in advanced organic synthesis, enabling the efficient introduction of the benzo[c]thiophene moiety into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders or as kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and pesticides with novel modes of action.
• Material Science Research: Serves as a monomer or functionalization agent for creating polymers and organic electronic materials with specific optoelectronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in catalytic systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	Benzo[C]Thiophene-1-Carbonyl Chloride (9Ci)
CAS No.	133179-63-2
Molecular Formula	C9H5ClOS
Molecular Weight	196.65 g/mol
Synonyms	1-Benzothiophene-1-carbonyl chloride; 1-Benzothiophene-1-carbonyl chloride (9CI); 1H-Benzo[c]thiophene-1-carbonyl chloride; 1-Benzo[c]thiophenecarbonyl chloride; 1-Carboxy-1-benzothiophene chloride; Benzo[c]thiophene-1-carbonyl chloride; Thianaphthene-1-carbonyl chloride
EINECS	Contact for details

Quality Control

Our Benzo[C]Thiophene-1-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as pre-clinical scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.