Description

Eprosartan CAS NO 133040-01-4 is a potent and selective angiotensin II receptor antagonist (ARB) used as an active pharmaceutical ingredient (API). This compound is critical for the development and manufacture of antihypertensive medications, offering a targeted mechanism of action to manage high blood pressure. It is primarily required by pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) involved in cardiovascular drug production.

Application

• Primary use as an Active Pharmaceutical Ingredient (API) in the formulation of antihypertensive drugs.
• Manufacturing of finished dosage forms, such as tablets and capsules, for the treatment of essential hypertension.
• Utilized in pharmaceutical research and development for studying angiotensin II receptor mechanisms.
• Reference standard in analytical laboratories for quality control and method validation.
• Used in preclinical and clinical studies to evaluate cardiovascular therapeutics.
• Sourcing for generic drug manufacturers producing cost-effective hypertension treatments.

Basic Information

Product Name	Eprosartan
CAS No.	133040-01-4
Molecular Formula	C23H24N2O4S
Molecular Weight	424.51 g/mol
Synonyms	Eprosartan; SKF-108566; (E)-3-[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]-2-(2-thienylmethyl)propenoic Acid; Teveten (Brand Name); Eprosartan Mesylate (salt form); Angiotensin II Type 1 Receptor Antagonist; (E)-α-[[2-Butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5-yl]methylene]-2-thiophenepropanoic Acid
EINECS	Contact for details

Quality Control

Our Eprosartan is manufactured under strict quality systems to meet the rigorous standards of the pharmaceutical industry. Production adheres to current Good Manufacturing Practice (GMP) guidelines, and the material is typically characterized against relevant pharmacopeial monographs. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each batch to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.