Description

Pentanedioyl Dichloride,2,2-Dimethyl- is a high-purity, reactive diacid chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its ability to introduce the sterically hindered 2,2-dimethylglutaroyl moiety, enabling the creation of novel polymers, pharmaceuticals, and specialty chemicals with tailored properties. It is essential for R&D chemists and production engineers in the pharmaceutical, agrochemical, and performance materials industries who require reliable, high-quality intermediates for scale-up and manufacturing.

Application

• Pharmaceutical Intermediate: Key starting material (KSM) or building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a hindered aliphatic chain.
• Polymer Chemistry: Monomer for the production of specialty polyamides, polyesters, and polyurethanes, imparting rigidity and specific thermal properties to the final polymer.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and plant growth regulators where the dimethyl-substituted structure enhances biological activity or stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Surface Modification Agent: Employed to functionalize surfaces of silica, polymers, or other materials to alter adhesion, wettability, or compatibility properties.
• Crosslinking Agent: Effective crosslinker for resins and coatings, improving hardness, chemical resistance, and durability.
• Organic Synthesis Reagent: A versatile reagent for acylation and condensation reactions in fine chemical and academic research laboratories.

Basic Information

Item	Detail
Product Name	Pentanedioyl Dichloride,2,2-Dimethyl-
CAS No.	133003-98-2
Molecular Formula	C7H10Cl2O2
Molecular Weight	197.06 g/mol
Synonyms	2,2-Dimethylglutaroyl dichloride; 2,2-Dimethylpentanedioyl dichloride; Glutaroyl dichloride, 2,2-dimethyl-; Dimethylglutaric acid dichloride; 2,2-Dimethyldiglutaryl chloride; α,α-Dimethylglutaroyl chloride; Pentanedioic acid, 2,2-dimethyl-, dichloride
EINECS	Contact for details

Quality Control

Our Pentanedioyl Dichloride,2,2-Dimethyl- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (IR, NMR), to ensure high chemical purity and consistency. Certificates of Analysis (COA) documenting identity, assay, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Acid Chloride Content	≥ 99.0% (by titration)
Related Substances (HPLC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.18 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.