Description

N(6)-Methyl-N(6)-(n-Threonylcarbonyl)Adenine is a chemically modified adenine derivative, a specialized nucleobase analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying nucleic acid interactions, enzyme mechanisms, and cellular signaling pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies engaged in the synthesis of novel therapeutic agents and molecular probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based therapeutics and antiviral agents.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies, particularly those involving adenosine receptors or modifying enzymes.
• Proteomics & Molecular Biology: Acts as a modified base in the design of oligonucleotide probes for studying gene expression and protein-nucleic acid interactions.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs targeting various diseases.
• Diagnostic Reagent Development: Potential component in the development of diagnostic assays and kits that require specific nucleotide analogs.

Basic Information

Product Name	N(6)-Methyl-N(6)-(n-Threonylcarbonyl)Adenine
CAS No.	132603-03-3
Molecular Formula	C12H16N6O4
Molecular Weight	308.30 g/mol
Synonyms	N6-Methyl-N6-(N-threonylcarbonyl)adenine; 6-(Methylamino)-9H-purin-6-ium-9-yl 2-amino-3-hydroxybutanoate; N6-Methyl-N6-(1-carboxy-2-hydroxypropyl)adenine; Modified Adenine Derivative; Threonylcarbonyl Methyl Adenine; N6-MTA; Research Grade Nucleobase Analog
EINECS	Contact for details

Quality Control

Our N(6)-Methyl-N(6)-(n-Threonylcarbonyl)Adenine is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals, and specifications can be aligned with customer-specific requirements for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.