Description

α-Methyl-4-(4-Carbamoyl-2-Thiazolyl)Benzeneacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and pharmaceutical importance. Its core value lies in its role as a critical precursor in the synthesis of more complex therapeutic agents, ensuring supply chain reliability for active pharmaceutical ingredient (API) manufacturers. This compound is essential for research and development laboratories, pharmaceutical synthesis units, and fine chemical producers targeting anti-inflammatory and analgesic drug pipelines.

Application

• Pharmaceutical Intermediate: Primary use as a key building block in the synthesis of novel NSAID candidates and related therapeutic molecules.
• Research & Development: Serves as a standard or starting material in medicinal chemistry for structure-activity relationship (SAR) studies and new drug discovery.
• Fine Chemical Synthesis: Utilized in multi-step organic synthesis to introduce specific thiazole and acetic acid functionalities into target compounds.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	α-Methyl-4-(4-Carbamoyl-2-Thiazolyl)Benzeneacetic Acid
CAS No.	132483-50-2
Molecular Formula	C₁₄H₁₂N₂O₃S
Molecular Weight	288.32 g/mol
Synonyms	2-[4-(4-Carbamoyl-1,3-thiazol-2-yl)phenyl]propanoic Acid; α-Methyl-4-(4-carbamoyl-2-thiazolyl)benzeneacetic acid; 4-(4-Carbamoyl-2-thiazolyl)-α-methylbenzeneacetic Acid; 2-(4-(4-Carbamoylthiazol-2-yl)phenyl)propionic Acid; A Related NSAID Intermediate; UNII-9P6K5P8H4F; 9P6K5P8H4F
EINECS	Contact for details

Quality Control

Our α-Methyl-4-(4-Carbamoyl-2-Thiazolyl)Benzeneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.