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2,3,4,6-Tetra-o-Benzoyl-β-D-Glucopyranosyl Isothiocyanate CAS NO 132413-50-4


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CAS No.:132413-50-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2,3,4,6-Tetra-o-Benzoyl-β-D-Glucopyranosyl Isothiocyanate is a key protected glycosyl donor and building block in synthetic carbohydrate chemistry. This compound is essential for the efficient and stereoselective synthesis of thioglycosides, which are crucial intermediates for developing glycoconjugates and bioactive molecules. It is primarily used by research scientists and process chemists in pharmaceutical R&D, agrochemical discovery, and advanced material science for constructing complex carbohydrate scaffolds.

Application

  • Pharmaceutical Intermediate: Critical building block for the synthesis of novel thioglycoside-based drug candidates and prodrugs.
  • Glycoconjugate Synthesis: Used in the preparation of complex oligosaccharides, glycopeptides, and glycolipids for biological studies.
  • Agrochemical Research: Serves as a precursor in developing carbohydrate-derived pesticides and plant growth regulators.
  • Chemical Biology Probes: Enables the creation of labeled glycosides for studying carbohydrate-protein interactions and enzyme mechanisms.
  • Material Science: Acts as a monomer or cross-linker in the development of specialty polymers with unique surface properties.
  • Process Chemistry: Employed in scalable routes for the manufacture of active pharmaceutical ingredients (APIs) with carbohydrate motifs.

Basic Information

Item Details
Product Name 2,3,4,6-Tetra-o-Benzoyl-β-D-Glucopyranosyl Isothiocyanate
CAS No. 132413-50-4
Molecular Formula C35H27NO9S
Molecular Weight 637.66 g/mol
Synonyms 2,3,4,6-Tetra-O-benzoyl-β-D-glucopyranosyl isothiocyanate; Tetra-O-benzoyl-β-D-glucosyl isothiocyanate; 1-Isothiocyanato-2,3,4,6-tetra-O-benzoyl-β-D-glucopyranose; Glucopyranosyl isothiocyanate, 2,3,4,6-tetra-O-benzoyl-, β-D-; Benzoylated glucosyl isothiocyanate; Protected glucosyl isothiocyanate donor
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Quality Control

Our 2,3,4,6-Tetra-o-Benzoyl-β-D-Glucopyranosyl Isothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under inert atmosphere or with desiccant to maintain stability and prevent decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation [α]²⁰D -15° to -25° (c=1 in CHCl₃)
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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