Description

Levocloperastineih is the levo-isomer of cloperastine, a non-opioid antitussive agent. This specific enantiomer is of significant interest in pharmaceutical development due to its targeted pharmacological activity and potential for an improved therapeutic profile. It is primarily utilized in advanced research and development for creating next-generation cough suppressants. Global B2B clients in the pharmaceutical and fine chemical sectors source this compound for its critical role in enantioselective synthesis and high-purity active pharmaceutical ingredient (API) manufacturing.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of advanced antitussive medications.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for formulating new enantiomerically pure cough suppressants with potentially reduced side effects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Pharmacological Research: Utilized in preclinical and clinical studies to investigate the specific efficacy and pharmacokinetics of the levo-isomer.
• Fine Chemical Synthesis: Applied in custom synthesis and contract manufacturing for producing specialized chiral compounds.

Basic Information

Product Name	Levocloperastineih
CAS No.	132301-89-4
Molecular Formula	C20H24ClNO
Molecular Weight	329.87 g/mol
Synonyms	(-)-Cloperastine; Levocloperastine; (S)-Cloperastine; 1-[2-[(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine, (S)-; LEVOTUSS; Cloperastine Impurity; Cloperastine Related Compound; Antitussive Agent
EINECS	Contact for details

Quality Control

Our Levocloperastineih is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.5%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.