Description

[R-(R*,R*)]-(1,2-Dihydroxypropyl)Phosphonic Acid CAS NO 132125-60-1 is a high-purity, stereochemically defined organophosphorus compound. This compound is valued for its unique chelating properties and its role as a versatile chiral intermediate in advanced chemical synthesis. It is essential for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in classes requiring phosphonate functionality.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its chelating properties enhance efficacy.
• Metal Chelation & Scale Inhibition: Functions as an effective chelating agent in water treatment formulations and industrial cleaning products to control metal ions and prevent scale.
• Ligand for Catalysis: Serves as a precursor or ligand in asymmetric catalysis, enabling stereoselective transformations in fine chemical manufacturing.
• Biochemical Research: Employed in biochemical studies as an analog of natural phosphates or as a tool to investigate enzyme mechanisms.
• Polymer Additive: Can be incorporated as a functional monomer or additive to impart flame retardancy or metal-binding characteristics to polymers.

Basic Information

Item	Details
Product Name	[R-(R*,R*)]-(1,2-Dihydroxypropyl)Phosphonic Acid
CAS No.	132125-60-1
Molecular Formula	C₃H₉O₅P
Molecular Weight	156.07 g/mol
Synonyms	(R,R)-1,2-Dihydroxypropylphosphonic Acid; (2R,3R)-1,2-Dihydroxy-3-phosphonopropane; (R,R)-DHPPA; Fosfomycin Intermediate; (R,R)-1-Hydroxy-2-(hydroxymethyl)ethylphosphonic Acid; (2R,3R)-3-Hydroxy-2-(hydroxymethyl)propylphosphonic Acid; L,L-Isomer of 1,2-Dihydroxypropylphosphonic Acid
EINECS	Contact for details

Quality Control

Every batch of [R-(R*,R*)]-(1,2-Dihydroxypropyl)Phosphonic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. Our quality protocols are designed to meet the stringent requirements of pharmaceutical and fine chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.