Description

6-S-(4-Chlorophenyl)-6-Thio-Inosine 2',3',5'-Triacetate is a chemically modified nucleoside derivative, serving as a key synthetic intermediate in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel antiviral and anticancer agents, where its modified structure allows for targeted biological activity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside-based therapeutics.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside analog drugs targeting viral infections and oncology.
• Antiviral Agent Research: Used in the development and study of potential antiviral compounds, particularly against DNA viruses.
• Anticancer Drug Discovery: Serves as a precursor in creating experimental chemotherapeutic agents that interfere with cellular DNA/RNA synthesis.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies related to purine metabolism and nucleoside processing.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize the potency and selectivity of therapeutic candidates.
• Fine Chemical Synthesis: Acts as a specialized intermediate for custom synthesis and contract manufacturing of high-value, complex molecules.

Basic Information

Product Name	6-S-(4-Chlorophenyl)-6-Thio-Inosine 2',3',5'-Triacetate
CAS No.	132089-80-6
Molecular Formula	C22H21ClN4O7S
Molecular Weight	520.94 g/mol
Synonyms	6-[(4-Chlorophenyl)thio]-9-[(2R,3R,4R,5R)-3,4-diacetyloxy-5-(acetyloxymethyl)oxolan-2-yl]purine; 6-S-(p-Chlorophenyl)-6-thioinosine 2',3',5'-triacetate; 6-(4-Chlorophenylthio)inosine 2',3',5'-tri-O-acetate; Inosine, 6-[(4-chlorophenyl)thio]-, 2',3',5'-triacetate; 6-(4-Chlorophenylmercapto)inosine triacetate; 6-S-(4-Chlorophenyl)thioinosine triacetate; 6-(p-Chlorophenylthio)purine riboside triacetate
EINECS	Contact for details

Quality Control

Our 6-S-(4-Chlorophenyl)-6-Thio-Inosine 2',3',5'-Triacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.