Description

5-Hydroxy Lansoprazole is a key pharmaceutical intermediate and metabolite of the proton pump inhibitor Lansoprazole. This compound is critical for research and development in the pharmaceutical industry, particularly in the study of drug metabolism, pharmacokinetics, and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions focused on gastroenterology and metabolic pathways.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis and development of proton pump inhibitor (PPI) drugs and their derivatives.
• Metabolite Reference Standard: Used as a certified reference material (CRM) in bioanalytical studies for quantifying Lansoprazole and its metabolites in biological samples.
• Pharmacokinetics & Metabolism Research: Essential for in-vitro and in-vivo studies to understand the absorption, distribution, metabolism, and excretion (ADME) profile of Lansoprazole.
• Impurity Standard: Serves as a known impurity standard in the quality control and stability testing of Lansoprazole API and finished dosage forms.
• Analytical Method Development: Employed for developing and validating HPLC, LC-MS, and other chromatographic methods in pharmaceutical analysis.
• Preclinical & Clinical Research: Supports drug discovery and development programs targeting acid-related disorders.

Basic Information

Product Name	5-Hydroxy Lansoprazole
CAS No.	131926-98-2
Molecular Formula	C16H14F3N3O3S
Molecular Weight	401.36 g/mol
Synonyms	5-Hydroxylansoprazole; Lansoprazole 5-Hydroxy Metabolite; 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazol-5-ol; AG-2000; AG 2000; AG2000; (RS)-5-Hydroxy Lansoprazole
EINECS	Contact for details

Quality Control

Our 5-Hydroxy Lansoprazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and MS, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatograms and full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.