Description

2-[2-(4-Chlorophenyl)Ethoxy]Adenosine is a synthetic adenosine derivative with a modified ribose moiety, designed for high-affinity interaction with specific adenosine receptor subtypes. This compound is a critical research-grade biochemical for investigating purinergic signaling pathways and their modulation. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel therapeutic agents targeting cardiovascular, neurological, and inflammatory conditions.

Application

• Pharmacological Research: A key reference standard and tool compound for studying adenosine A1 and A2A receptor activity, selectivity, and downstream signaling effects.
• Drug Discovery & Development: Serves as a lead compound or intermediate in the synthesis of novel adenosine receptor agonists/antagonists for therapeutic applications.
• Biochemical Assays: Used in high-throughput screening (HTS), radioligand binding assays, and functional cellular assays to characterize receptor-ligand interactions.
• Academic & Clinical Research: Facilitates fundamental research into the role of adenosine receptors in ischemia-reperfusion injury, neuroprotection, sleep regulation, and immune response modulation.
• Analytical Standard: Employed as a certified reference material (CRM) in HPLC, LC-MS, and NMR for method development, validation, and quality control of related substances.

Basic Information

Product Name	2-[2-(4-Chlorophenyl)Ethoxy]Adenosine
CAS No.	131865-88-8
Molecular Formula	C18H20ClN5O4
Molecular Weight	405.83 g/mol
Synonyms	2-(2-(4-Chlorophenoxy)ethoxy)adenosine; 2-(2-(p-Chlorophenoxy)ethoxy)adenosine; 2-O-(2-(4-Chlorophenoxy)ethyl)adenosine; CVT-510; Tecadenoson; Adenosine, 2-[2-(4-chlorophenoxy)ethoxy]-; (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-([2-(4-chlorophenoxy)ethoxy]methyl)oxolane-3,4-diol
EINECS	Contact for details

Quality Control

Every batch of 2-[2-(4-Chlorophenyl)Ethoxy]Adenosine is manufactured and tested under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and reliability for your research. Our standard quality commitment includes identity confirmation by spectroscopic methods (NMR, IR, MS), purity determination by HPLC, and control of related substances. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.