Description

(3,5-Difluoro-2-Methoxy-Phenyl)-Methanol is a versatile fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms and the methoxy and hydroxymethyl functional groups, which enable precise molecular modifications. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the difluoromethoxy phenyl moiety imparts desirable biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of novel organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The aromatic ring can be further functionalized via Suzuki, Heck, or other palladium-catalyzed cross-coupling reactions.
• Chemical Research: A valuable reagent for exploring new fluorination methodologies and constructing complex, fluorinated molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	(3,5-Difluoro-2-Methoxy-Phenyl)-Methanol
CAS No.	131782-51-9
Molecular Formula	C8H8F2O2
Molecular Weight	174.15 g/mol
Synonyms	(3,5-Difluoro-2-methoxyphenyl)methanol; 2-Methoxy-3,5-difluorobenzyl alcohol; 3,5-Difluoro-2-methoxybenzenemethanol; (3,5-Difluoro-2-methoxyphenyl)carbinol; Benzenemethanol, 3,5-difluoro-2-methoxy-; 131782-51-9; 3,5-Difluoro-o-vanillyl alcohol
EINECS	Contact for details

Quality Control

Our (3,5-Difluoro-2-Methoxy-Phenyl)-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.