Description

8-Amino-5'-Iodoguanosine is a modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block for the synthesis of oligonucleotides and probes, enabling precise molecular targeting and diagnostic applications. It is primarily utilized by researchers and manufacturers in the fields of nucleic acid chemistry, antiviral drug discovery, and molecular diagnostics.

Application

• Oligonucleotide Synthesis: A key precursor for incorporating modified bases into DNA/RNA strands for research and therapeutic applications.
• Antiviral Research: Investigated as a potential scaffold or intermediate in the development of novel nucleoside analog antiviral agents.
• Molecular Probe Development: Used to create labeled probes for fluorescence in situ hybridization (FISH) and other detection techniques due to the iodine moiety.
• Biochemical Research: Employed in studies of enzyme mechanisms, nucleic acid structure, and function.
• Diagnostic Reagent Manufacturing: A component in the production of specialized reagents for diagnostic kits.
• Radiopharmaceutical Precursor: The iodine atom provides a potential site for radioiodination, making it a candidate for developing imaging agents.

Basic Information

Product Name	8-Amino-5'-Iodoguanosine
CAS No.	131635-07-9
Molecular Formula	C10H13IN6O5
Molecular Weight	424.15 g/mol
Synonyms	5'-Iodo-8-aminoguanosine; 8-Amino-5'-iodoguanosine; Guanosine, 8-amino-5'-iodo-; 8-Amino-5'-iodo-9-β-D-ribofuranosyl-9H-guanine; 8-Amino-5'-iodo-guanosine; 8-NH2-5'-I-Guo
EINECS	Contact for details

Quality Control

Our 8-Amino-5'-Iodoguanosine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.