Description

Cyclopentanecarbonyl Chloride, 2-Hydroxy-, (1R-Cis)- (9Ci) is a high-purity chiral building block of significant interest in advanced organic synthesis. Its value lies in its functionalized cyclopentane ring and reactive acid chloride group, which enable the stereoselective construction of complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals where precise stereochemistry is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, cardiovascular diseases, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its stereochemistry can influence biological activity and environmental selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for the preparation of chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical and Specialty Material Production: Employed in the manufacture of complex fragrance molecules, advanced polymers, and liquid crystals.
• Academic and Contract Research: A valuable reagent for methodological development in organic chemistry and for producing reference standards in analytical laboratories.

Basic Information

Product Name	Cyclopentanecarbonyl Chloride, 2-Hydroxy-, (1R-Cis)- (9Ci)
CAS No.	131622-58-7
Molecular Formula	C6H9ClO2
Molecular Weight	148.59 g/mol
Synonyms	(1R,2S)-2-Hydroxycyclopentanecarbonyl chloride; (1R,2S)-2-Hydroxy-1-cyclopentanecarboxylic acid chloride; (1R-cis)-2-Hydroxycyclopentanecarboxylic acid chloride; cis-(1R,2S)-2-Hydroxycyclopentanecarbonyl chloride; (1R,2S)-rel-2-Hydroxycyclopentanecarbonyl chloride; 2-Hydroxycyclopentanecarbonyl chloride, (1R-cis)-; Cyclopentanecarbonyl chloride, 2-hydroxy-, (1R-cis)-
EINECS	Contact for details

Quality Control

Our Cyclopentanecarbonyl Chloride, 2-Hydroxy-, (1R-Cis)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data for chiral purity (enantiomeric excess), chemical purity (HPLC/GC), identity confirmation (IR, NMR), and other critical parameters. We are committed to meeting the stringent requirements of pharmaceutical development and other high-value industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; therefore, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and away from incompatible materials. Use appropriate corrosion-resistant storage equipment.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.