Description

2-(2-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is a versatile fluorinated organic building block characterized by its diol functionality and aromatic fluorophenyl group. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is primarily sought by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel central nervous system (CNS) drugs and other therapeutic agents.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced bioactivity and stability.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Employed to introduce fluorinated aromatic units into polymer backbones, altering material properties like thermal stability and solubility.
• Academic & R&D: A valuable compound for methodological studies in organic synthesis, particularly in stereoselective reactions and fluorine chemistry.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	2-(2-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol
CAS No.	131506-00-8
Molecular Formula	C10H13FO3
Molecular Weight	200.21 g/mol
Synonyms	2-(2-Fluorophenyl)-2-(hydroxymethyl)-1,3-propanediol; 2-(Hydroxymethyl)-2-(2-fluorophenyl)propane-1,3-diol; 1,3-Propanediol, 2-(2-fluorophenyl)-2-(hydroxymethyl)-; α-(Hydroxymethyl)-α-(2-fluorophenyl)-1,3-propanediol; (2-Fluorophenyl)(hydroxymethyl)propanediol; Fluorophenyl propanediol derivative
EINECS	Contact for details

Quality Control

Our 2-(2-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.