Description

2-(3-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is a versatile fluorinated organic building block characterized by a phenyl ring substituted with a fluorine atom and a triol functional group. This unique structure makes it a valuable intermediate for synthesizing more complex molecules, particularly in the pharmaceutical and agrochemical sectors where the introduction of fluorine can dramatically alter a compound's biological activity, metabolic stability, and lipophilicity. It is primarily sought after by research chemists and process development scientists working on novel active ingredients, specialty polymers, and advanced material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, especially for CNS (Central Nervous System) and anti-inflammatory targets where the fluorophenyl moiety is pharmacologically relevant.
• Agrochemical Synthesis: Used in constructing advanced herbicide and pesticide molecules, leveraging the fluorine atom to enhance bioavailability and environmental persistence.
• Ligand and Catalyst Development: The triol group provides multiple coordination sites, making it useful for creating chiral ligands for asymmetric catalysis or metal-organic frameworks (MOFs).
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polyesters, polyurethanes, and epoxy resins with modified thermal and chemical resistance properties.
• Material Science Research: Employed in the development of novel fluorinated materials for coatings, electronics, and optics due to its ability to impart specific surface characteristics.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for studying biological processes and diagnostics.

Basic Information

Product Name	2-(3-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol
CAS No.	131505-99-2
Molecular Formula	C10H13FO3
Molecular Weight	200.21 g/mol
Synonyms	1,3-Propanediol, 2-(3-fluorophenyl)-2-(hydroxymethyl)-; 2-(Hydroxymethyl)-2-(3-fluorophenyl)-1,3-propanediol; 3-Fluorophenyl Neopentyl Glycol; 2-(3-Fluorophenyl)-2-(hydroxymethyl)propane-1,3-diol; (3-Fluorophenyl)bis(hydroxymethyl)methanol; α,α-Bis(hydroxymethyl)-3-fluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Fluorophenyl)-2-(Hydroxymethyl)Propane-1,3-Diol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to support compliance with cGMP and ISO 9001 standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.