Description

Pradimicin Fb is a potent antifungal antibiotic belonging to the pradimicin family, a class of compounds known for their unique carbohydrate-binding properties. This compound is valued for its significant research and development potential in combating fungal infections, particularly against strains resistant to conventional therapies. It is primarily utilized by pharmaceutical researchers, biotechnology firms, and academic institutions focused on novel antimicrobial discovery and mechanism of action studies.

Application

• Antifungal Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) in the discovery of new antifungal agents.
• Mechanistic Studies: Used to investigate the unique calcium-dependent, lectin-like mode of action against fungal cell wall mannans.
• Biochemical Assays: Employed in in vitro susceptibility testing and high-throughput screening platforms to evaluate antifungal activity.
• Pharmaceutical Intermediates: Acts as a critical building block for the semi-synthesis of novel pradimicin analogs with improved pharmacological profiles.
• Microbiology Research: Applied in studies targeting Candida, Aspergillus, and other pathogenic fungi to understand resistance mechanisms.

Basic Information

Product Name	Pradimicin Fb
CAS No.	131426-61-4
Molecular Formula	C₆₀H₈₅NO₂₈
Molecular Weight	1280.3 g/mol
Synonyms	Pradimicin FB; Pradimicin F B; Benanomicin Fb; Antibiotic BMS-181184; BMS 181184; (1S,3aS,5aR,5bS,7S,9R,11aR,11bS,13aR,13bS)-7-[(6-Deoxy-4-O-(6-deoxy-4-O-[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-α-L-mannopyranosyl)-α-L-mannopyranosyl)oxy]-9,11b-dihydroxy-1-[(1R)-1-hydroxyethyl]-5a,5b,8,8,11a,13b-hexamethyl-3,13-dioxo-1,2,3a,4,5,5a,5b,6,7,8,9,10,11,11a,11b,12,13,13a,13b-octadecahydrocyclopenta[a]chrysen-3a-yl 3-amino-3,6-dideoxy-β-D-mannopyranoside
EINECS	Contact for details

Quality Control

Our Pradimicin Fb is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification (NMR, IR, MS), and microbiological assay for potency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤5.0%
Potency (Microbiological Assay)	850-1150 µg/mg
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.