Description

1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci) is a high-value, heterocyclic acid chloride derivative that serves as a critical synthetic building block in advanced organic chemistry. Its significance lies in its reactivity as an acylating agent, enabling the efficient introduction of the tetrahydrobenzimidazole-5-carbonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemical intermediates. The CAS number for this compound is 131020-44-5.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides, herbicides, and fungicides with specific biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent for creating specialized polymers with unique thermal or chemical resistance properties.
• Ligand and Catalyst Development: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized for labeling and modifying biomolecules to study biological pathways and protein functions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro- (9Ci)
CAS No.	131020-44-5
Molecular Formula	C9H9ClN2O
Molecular Weight	196.63 g/mol
Synonyms	4,5,6,7-Tetrahydro-1H-benzimidazole-5-carbonyl chloride; 4,5,6,7-Tetrahydro-1H-benzimidazole-5-carboxylic acid chloride; 5-(Chlorocarbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole; Tetrahydrobenzimidazole-5-carbonyl chloride; 1H-Benzimidazole-5-carbonyl chloride, 4,5,6,7-tetrahydro-; 131020-44-5
EINECS	Contact for details

Quality Control

Our production of 1H-Benzimidazole-5-Carbonyl Chloride, 4,5,6,7-Tetrahydro- adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to supply chain reliability and batch-to-batch consistency supports our clients' R&D and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.