Description

Cyclopentanecarbonyl Chloride, 2-Methoxy-, (1S-Trans)- (9Ci) is a high-purity, chiral building block of significant interest in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Asymmetric Synthesis: Used as a precursor for introducing the (1S-Trans)-2-methoxycyclopentane moiety in stereoselective reactions to create enantiomerically pure compounds.
• Agrochemical Research: Serves as a building block in the synthesis of novel, chiral pesticides and herbicides with potentially improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic chemistry applications.
• Material Science: Potential use in the synthesis of advanced polymers and liquid crystals where specific chirality influences material properties.

Basic Information

Product Name	Cyclopentanecarbonyl Chloride, 2-Methoxy-, (1S-Trans)- (9Ci)
CAS No.	130980-60-8
Molecular Formula	C7H11ClO2
Molecular Weight	162.62 g/mol
Synonyms	(1S,2R)-2-Methoxycyclopentanecarbonyl chloride; (1S-trans)-2-Methoxycyclopentanecarbonyl chloride; trans-2-Methoxycyclopentanecarbonyl chloride; (1S,2R)-2-Methoxy-1-cyclopentanecarbonyl chloride; 2-Methoxycyclopentanecarbonyl chloride, (1S-trans)-; Cyclopentanecarbonyl chloride, 2-methoxy-, (1S-trans)-
EINECS	Contact for details

Quality Control

Our production of Cyclopentanecarbonyl Chloride, 2-Methoxy-, (1S-Trans)- (9Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chiral purity, which is critical for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles. We are committed to meeting the exacting requirements of pharmaceutical R&D and can provide material with specifications tailored to your process.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.