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3-(2,4,5-Trifluoro-Phenyl)-Propan-1-Ol CAS NO 130887-16-0
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CAS No.:130887-16-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-(2,4,5-Trifluoro-Phenyl)-Propan-1-Ol is a high-purity fluorinated aromatic alcohol building block, essential for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced materials. Its trifluoromethylphenyl moiety provides unique electronic and steric properties that are critical for modulating the bioavailability and metabolic stability of target molecules. This compound is primarily utilized by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms into their molecular architectures.
Application
- Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
- Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atoms enhance biological activity and environmental persistence.
- Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
- Polymer Modification: Incorporated as a monomer or chain modifier to create specialty polymers with enhanced chemical resistance and thermal properties.
- Organic Synthesis Building Block: Employed in cross-coupling reactions, reductions, and functional group transformations in complex multi-step syntheses.
- Fluorine Chemistry Research: A valuable standard and starting material for academic and industrial research exploring new fluorination methodologies and structure-activity relationships.
Basic Information
| Product Name | 3-(2,4,5-Trifluoro-Phenyl)-Propan-1-Ol |
| CAS No. | 130887-16-0 |
| Molecular Formula | C9H9F3O |
| Molecular Weight | 190.16 g/mol |
| Synonyms | 3-(2,4,5-Trifluorophenyl)propan-1-ol; 2,4,5-Trifluorobenzene propanol; 3-(2,4,5-Trifluorophenyl)-1-propanol; 1-Propanol, 3-(2,4,5-trifluorophenyl)-; (2,4,5-Trifluorophenyl)propyl alcohol; 3-(2,4,5-Trifluorophenyl)propyl alcohol; 130887-16-0; 3-(2,4,5-Trifluorophenyl)propanol |
| EINECS | Contact for details |
Quality Control
Our 3-(2,4,5-Trifluorophenyl)propan-1-ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and heat sources. For long-term storage, consider an inert atmosphere to maintain optimal purity.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Specific Impurities (HPLC) | Individual ≤ 0.5%, Total ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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