Description

(3'-Hydroxy)-3,N(4)-Benzetheno-1'-Deoxycytidine 3'-Phosphate is a chemically modified nucleoside phosphate derivative, a critical building block in advanced oligonucleotide synthesis and medicinal chemistry research. Its primary value lies in enabling the development of novel antisense oligonucleotides, aptamers, and other therapeutic nucleic acid analogs with enhanced stability and binding properties. This high-purity intermediate is essential for pharmaceutical R&D teams, diagnostic developers, and academic institutions focused on next-generation genetic therapies and molecular biology tools.

Application

• Antisense Oligonucleotide (ASO) Synthesis: A key phosphoramidite precursor for constructing therapeutic oligonucleotides designed to modulate gene expression.
• Aptamer Development: Used in the solid-phase synthesis of nucleic acid aptamers for diagnostic and targeted therapeutic applications.
• Research Grade Biochemicals: Serves as a specialized reagent in academic and industrial laboratories studying nucleic acid chemistry and metabolism.
• Pharmaceutical Intermediate: An important building block in the research and development of novel nucleoside-based antiviral or anticancer prodrugs.
• Molecular Probe Synthesis: Incorporated into labeled probes for diagnostic assays and genomic research due to its modified structure.

Basic Information

Product Name	(3'-Hydroxy)-3,N(4)-Benzetheno-1'-Deoxycytidine 3'-Phosphate
CAS No.	130882-58-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(2-Deoxy-3-O-phosphono-β-D-erythro-pentofuranosyl)-3,N4-benzethenocytosine; 3,N4-Benzocytosine 2'-deoxyriboside 3'-phosphate; 3'-Phosphorylated 3,N4-Benzocytidine derivative; Modified dCMP analog; Benzetheno-deoxycytidine monophosphate; Bz-dC 3'-phosphate
EINECS	Contact for details

Quality Control

Our (3'-Hydroxy)-3,N(4)-Benzetheno-1'-Deoxycytidine 3'-Phosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for sensitive research applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC purity profiles, identity confirmation (NMR, MS), and impurity analysis. Our quality commitment aligns with the standards required for pharmaceutical R&D and advanced biochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.