Description

Inosine, 2'',3''-Dideoxy-, 5''-Acetate is a chemically modified nucleoside derivative, specifically an acetate ester of a dideoxyinosine analog. This compound is a crucial high-purity intermediate in advanced pharmaceutical research and synthesis. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of antiviral agents and nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and viral replication mechanisms.
• Antiviral Agent Development: Serves as a core structural component for creating novel analogs targeting viruses such as HIV and hepatitis.
• Pro-drug Synthesis: The acetate group can be utilized in pro-drug strategies to enhance the bioavailability of active nucleoside compounds.
• Reference Standard: Employed as a certified reference material (CRM) in analytical laboratories for method development and quality control of related APIs.
• Organic Synthesis: Acts as a specialized chiral synthon for constructing complex molecules in medicinal chemistry programs.

Basic Information

Product Name	Inosine, 2'',3''-Dideoxy-, 5''-Acetate
CAS No.	130676-58-3
Molecular Formula	C12H14N4O5
Molecular Weight	294.26 g/mol
Synonyms	2',3'-Dideoxyinosine 5'-acetate; 5'-O-Acetyl-2',3'-dideoxyinosine; ddI 5'-Acetate; 9-[(2R,5S)-5-(Acetyloxy)-2-(hydroxymethyl)oxolan-3-yl]-3H-purin-6-one; 2',3'-Dideoxyinosine acetate ester; Inosine, 2',3'-dideoxy-, 5'-acetate; 5'-Acetyl-2',3'-dideoxyinosine
EINECS	Contact for details

Quality Control

Our Inosine, 2'',3''-Dideoxy-, 5''-Acetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent product degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.