Description

1-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, Exo- (9Ci) is a high-value, reactive bicyclic building block used in advanced organic synthesis. This compound matters as a key chiral intermediate for constructing complex nitrogen-containing molecular architectures, offering precise stereochemical control. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its bicyclic structure imparts specific biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the synthesis of specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetic Chemistry: Employed to introduce constrained, bicyclic amino acid analogs into peptides to enhance metabolic stability and binding affinity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry and for exploring new chemical space in corporate and university laboratories.

Basic Information

Item	Details
Product Name	1-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, Exo- (9Ci)
CAS No.	130513-77-8
Molecular Formula	C7H10ClNO
Molecular Weight	159.61 g/mol
Synonyms	Exo-1-Azabicyclo[2.2.1]heptane-3-carbonyl chloride; (1R,2S,4S)-1-Azabicyclo[2.2.1]heptane-2-carbonyl chloride; 2-Norbornane-2-carbonyl chloride, 1-aza-, endo- (8CI); Bicyclo[2.2.1]heptane-2-carbonyl chloride, 1-aza-, (1R,2S,4S)-rel-; 1-Azabicyclo[2.2.1]heptane-3-carbonyl chloride, exo-; 3-Carbamoyl-1-azabicyclo[2.2.1]heptane hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[2.2.1]Heptane-3-Carbonyl Chloride, Exo- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with exacting R&D standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and highly volatile; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and moisture uptake. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (exo-isomer)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.