Description

Cyclobutanecarbonyl Chloride, 3,3-Dimethoxy- (9Ci) is a specialized organic building block featuring a reactive acid chloride functional group on a cyclobutane ring substituted with dimethoxy groups. This compound matters as a critical intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research, where its unique strained-ring structure can impart specific biological activity or modify physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for constructing novel active ingredients and exploring new chemical spaces.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring specific conformational rigidity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or insecticides, where the cyclobutane moiety can enhance stability or bioavailability.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers with unique thermal or mechanical properties.
• Ligand and Catalyst Development: Employed to create novel chiral ligands or organometallic catalysts for asymmetric synthesis applications.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules to study protein interactions or cellular pathways.
• Academic & Institutional Research: A valuable reagent for methodological studies in organic synthesis, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclobutanecarbonyl Chloride, 3,3-Dimethoxy- (9Ci)
CAS No.	130233-76-0
Molecular Formula	C7H11ClO3
Molecular Weight	178.62 g/mol
Synonyms	3,3-Dimethoxycyclobutanecarbonyl chloride; 3,3-Dimethoxycyclobutane-1-carbonyl chloride; Cyclobutane-1-carbonyl chloride, 3,3-dimethoxy-; 1-(Chlorocarbonyl)-3,3-dimethoxycyclobutane
EINECS	Contact for details

Quality Control

Our Cyclobutanecarbonyl Chloride, 3,3-Dimethoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation by moisture. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.