Description

Amphotericin B 2-Morpholinoethyl Amide Diaspartate is a chemically modified derivative of the potent polyene antifungal agent, Amphotericin B. This compound is engineered to enhance solubility and potentially reduce toxicity while retaining significant biological activity. It is primarily utilized in advanced pharmaceutical research and development, particularly for investigating novel antifungal therapies and targeted drug delivery systems. This high-purity intermediate is critical for researchers and manufacturers in the life sciences sector.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel antifungal drug candidates and prodrug formulations.
• Biomedical Research: Used in in vitro and in vivo studies to explore structure-activity relationships (SAR) of polyene antibiotics.
• Drug Delivery System Development: Investigated for incorporation into liposomal, nanoparticle, or conjugate-based delivery platforms to improve therapeutic index.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Amphotericin B 2-Morpholinoethyl Amide Diaspartate
CAS No.	130176-10-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Amphotericin B Morpholinoethyl Amide Diaspartate; Amphotericin B 2-Morpholinoethylamide Diaspartate; 2-Morpholinoethyl Amide of Amphotericin B Diaspartate; AmB-MEA Diaspartate; Amphotericin B Derivative (Diaspartate Salt); CAS 130176-10-2
EINECS	Contact for details

Quality Control

Our Amphotericin B 2-Morpholinoethyl Amide Diaspartate is manufactured under controlled conditions to ensure high purity and consistency. Each batch undergoes rigorous analytical testing, including HPLC for assay and purity determination, and is supported by a comprehensive Certificate of Analysis (COA). We adhere to stringent internal quality standards suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.