Description

2H-1-Benzopyran-2-Carbonylchloride,3,4-Dihydro-,(2S)-(9Ci) is a chiral, enantiomerically pure chemical intermediate of significant importance in advanced organic synthesis. This compound matters because its reactive acid chloride functionality and defined stereochemistry make it a critical building block for constructing complex, biologically active molecules with high precision. Pharmaceutical and agrochemical research organizations need this high-purity intermediate for the development of novel active ingredients, particularly in areas requiring specific chiral induction.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of potential drug candidates, including cardiovascular and central nervous system (CNS) agents.
• Agrochemical Research: Used in constructing chiral scaffolds for novel herbicides, fungicides, and plant growth regulators.
• Asymmetric Synthesis: Serves as a versatile starting material for introducing the dihydrobenzopyran moiety with (S)-configuration into target molecules.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of specialty chemicals for research and development.
• Ligand and Catalyst Development: Potential precursor for creating chiral ligands used in asymmetric catalysis.

Basic Information

Product Name	2H-1-Benzopyran-2-Carbonylchloride,3,4-Dihydro-,(2S)-(9Ci)
CAS No.	130049-78-4
Molecular Formula	C10H9ClO2
Molecular Weight	196.63 g/mol
Synonyms	(S)-3,4-Dihydro-2H-1-benzopyran-2-carbonyl chloride; (2S)-3,4-Dihydro-2H-chromene-2-carbonyl chloride; (S)-Chroman-2-carbonyl chloride; (S)-2-Chromancarbonyl chloride; (S)-Dihydro-2H-1-benzopyran-2-carbonyl chloride; (2S)-3,4-Dihydro-2H-1-benzopyran-2-carbonyl chloride; (S)-2-Carboxychromanoyl chloride
EINECS	Contact for details

Quality Control

Our production of 2H-1-Benzopyran-2-Carbonylchloride,3,4-Dihydro-,(2S)-(9Ci) adheres to stringent quality protocols suitable for advanced R&D and pre-clinical applications. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specific results for chiral purity, chemical purity, and related substances are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.