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2',3'-Dideoxycytidine Diphosphoethanolamine CAS NO 130036-23-6


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CAS No.:130036-23-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2',3'-Dideoxycytidine Diphosphoethanolamine is a specialized nucleotide analog derivative, a crucial building block in advanced biochemical research and development. This compound is valued for its role in the synthesis of modified oligonucleotides and as a key intermediate in the study of nucleic acid metabolism and enzyme mechanisms. It is primarily utilized by research institutions and pharmaceutical companies engaged in antiviral drug discovery, molecular biology, and the development of diagnostic probes.

Application

  • Antiviral Research Intermediate: Serves as a critical precursor in the synthesis and study of nucleoside analogs targeting viral polymerases.
  • Oligonucleotide Synthesis: Used as a modified monomer for incorporating specific functionalities into synthetic DNA/RNA strands for therapeutic and diagnostic applications.
  • Biochemical Probe Development: Employed in creating labeled nucleotides to study enzyme kinetics, substrate specificity, and metabolic pathways.
  • Pharmaceutical R&D: Acts as a key starting material in the discovery and development stages of novel therapeutic agents.
  • Enzymology Studies: Utilized as a substrate or inhibitor to investigate the mechanisms of kinases, transferases, and other nucleic acid-modifying enzymes.

Basic Information

Product Name 2',3'-Dideoxycytidine Diphosphoethanolamine
CAS No. 130036-23-6
Molecular Formula C13H22N4O11P2
Molecular Weight 496.28 g/mol
Synonyms ddC Diphosphoethanolamine; 2',3'-Dideoxycytidine 5'-(trihydrogen diphosphate) P'→5'-ester with 2-aminoethanol; Cytidine, 2',3'-dideoxy-, 5'-(trihydrogen diphosphate), 5'→5'-ester with 2-aminoethanol; 5'-O-{[(2-Aminoethoxy)hydroxyphosphinyl]oxyphosphinyl}-2',3'-dideoxycytidine; Ethanolamine derivative of ddC diphosphate
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Quality Control

Our 2',3'-Dideoxycytidine Diphosphoethanolamine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (HPLC) Conforms to reference standard
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 5.0%
Solubility Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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