Description

5-Amino-7-((4-Nitrobenzyl)Thio)-3-(β-D-Ribofuranosyl)Pyrazolo(4,3-D )Pyrimidine CAS NO 129970-97-4 is a sophisticated nucleoside analog with a complex heterocyclic structure, designed for advanced research and development applications. This compound is valued for its role as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer research. It is primarily targeted at pharmaceutical R&D laboratories, biotechnology firms, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Medicinal Chemistry Research: Used as a reference standard or a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity.
• Biochemical Assay Development: Employed in the development of enzymatic assays to study the inhibition of specific viral or cellular polymerases.
• Academic Research: Utilized in university and institutional labs for fundamental studies on nucleoside metabolism and mechanism of action.
• Preclinical Development: Acts as a key material in the early-stage formulation and efficacy testing of potential new chemical entities (NCEs).

Basic Information

Product Name	5-Amino-7-((4-Nitrobenzyl)Thio)-3-(β-D-Ribofuranosyl)Pyrazolo(4,3-D )Pyrimidine
CAS No.	129970-97-4
Molecular Formula	C17H18N6O6S
Molecular Weight	434.43 g/mol
Synonyms	5-Amino-7-[(4-nitrobenzyl)sulfanyl]-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine; 5-Amino-7-((4-nitrobenzyl)thio)-3-(β-D-ribofuranosyl)pyrazolo[4,3-d]pyrimidine; 7-((4-Nitrobenzyl)thio)-3-(β-D-ribofuranosyl)-7H-pyrazolo[4,3-d]pyrimidin-5-amine; 129970-97-4; Pyrazolo[4,3-d]pyrimidine nucleoside derivative; 4-Nitrobenzylthio-substituted ribofuranosylpyrazolopyrimidine.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) documenting batch-specific results are available upon request. We adhere to a quality management system to ensure traceability and consistency for our research-grade chemical products.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.