Description

4-Oxo-5-Phosphononorvaline is a specialized phosphonic acid derivative that serves as a critical building block and research chemical in advanced organic synthesis. Its unique structure, featuring both a ketone and a phosphonate group, makes it a valuable intermediate for the development of enzyme inhibitors and bioactive compounds. This product is essential for pharmaceutical researchers, agrochemical developers, and academic institutions focused on medicinal chemistry and biochemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of glutamate analog enzyme inhibitors, particularly targeting glutamine synthetase and other metabolic enzymes.
• Medicinal Chemistry Research: Used as a scaffold for designing and developing novel drug candidates with potential neurological or metabolic activity.
• Biochemical Tool Compound: Employed in biochemical assays to study amino acid metabolism, enzyme kinetics, and inhibition pathways.
• Agrochemical Development: Serves as an intermediate for creating novel herbicidal or plant growth regulatory compounds.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for fundamental studies in organic synthesis and bioorganic chemistry.
• Peptidomimetic Synthesis: Building block for the construction of phosphonate-containing peptide analogs with enhanced stability or biological activity.

Basic Information

Item	Details
Product Name	4-Oxo-5-Phosphononorvaline
CAS No.	129938-34-7
Molecular Formula	C5H10NO6P
Molecular Weight	211.11 g/mol
Synonyms	5-Phosphono-4-oxonorvaline; (4-Oxo-5-phosphonopentanoic acid); DL-4-Oxo-5-phosphononorvaline; 4-Oxo-5-phosphonopentanoic Acid; Glutamate Analogue Inhibitor Intermediate; Phosphononorvaline Derivative
EINECS	Contact for details

Quality Control

Our 4-Oxo-5-Phosphononorvaline is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider using inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.