Description

(3β,20S)-21-Iodo-20-Methyl-Pregn-3-En-3-Ol Acetate CAS NO 129779-43-7 is a high-purity, synthetic steroid derivative characterized by its specific iodinated pregnane structure. This compound is of significant value as a critical pharmaceutical intermediate and a versatile research chemical for advanced organic synthesis. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and for conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for medicinal chemistry research, particularly in exploring new hormonal therapies or enzyme inhibitors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis using HPLC, GC-MS, or NMR.
• Biochemical Probe: Utilized in biological studies to investigate steroid receptor interactions and metabolic pathways due to its modified steroidal backbone.
• Process Chemistry: Employed in scaling up synthetic routes for pilot plant and commercial manufacturing of target molecules.

Basic Information

Product Name	(3β,20S)-21-Iodo-20-Methyl-Pregn-3-En-3-Ol Acetate
CAS No.	129779-43-7
Molecular Formula	C24H37IO2
Molecular Weight	484.46 g/mol
Synonyms	21-Iodo-20-methylpregn-3-en-3-ol acetate; 20-Methyl-21-iodopregn-3-en-3-ol acetate; (3β,20S)-21-Iodo-20-methylpregn-3-en-3-yl acetate; 3β-Acetoxy-21-iodo-20-methylpregn-5-ene; Pregn-5-ene-3β,21-diol, 20-methyl-, 3-acetate, 21-iodide; 129779-43-7; 21-Iodopregnane derivative
EINECS	Contact for details

Quality Control

Our (3β,20S)-21-Iodo-20-Methyl-Pregn-3-En-3-Ol Acetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.