Description

2,4,6-Trinitrophenyl-Uridine Diphosphate Galactose is a specialized nucleotide sugar derivative, a critical biochemical tool for studying glycosyltransferase enzymes and carbohydrate metabolism. Its core value lies in its role as a high-energy galactose donor, enabling precise enzymatic synthesis and labeling of complex glycoconjugates. This compound is essential for researchers and manufacturers in pharmaceutical development, glycobiology research, and the production of diagnostic reagents, where understanding and manipulating glycosylation pathways is paramount.

Application

• Glycosyltransferase Assays & Enzyme Characterization: Serves as a key substrate for in vitro assays to study the activity, kinetics, and specificity of galactosyltransferases.
• Glycoconjugate Synthesis: Used as an activated galactose donor for the enzymatic synthesis of oligosaccharides, glycopeptides, and glycolipids in research and development.
• Biochemical Research & Pathway Analysis: A vital tool in glycobiology for investigating galactosylation pathways, cell surface recognition, and carbohydrate-protein interactions.
• Diagnostic Reagent Development: Employed in the production and development of diagnostic kits and reagents that detect specific glycosyltransferase activities or carbohydrate-related biomarkers.
• Pharmaceutical R&D: Supports drug discovery efforts targeting glycosylation-related diseases, including cancer, immune disorders, and metabolic conditions.
• Labelling & Detection Studies: The trinitrophenyl group can facilitate detection, making it useful in tracer studies and analytical methods for tracking galactose incorporation.

Basic Information

Product Name	2,4,6-Trinitrophenyl-Uridine Diphosphate Galactose
CAS No.	129726-82-5
Molecular Formula	C₂₁H₂₅N₅O₂₁P₂
Molecular Weight	769.39 g/mol
Synonyms	TNP-UDP-Galactose; 2,4,6-Trinitrophenyl-UDP-Gal; UDP-Galactose-2',3',5'-tri(2,4,6-trinitrophenyl) ester; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with 2,3-bis-O-(2,4,6-trinitrophenyl)-α-D-galactopyranose, cyclic 4,6-(hydrogen phosphate); TNP-UDP-Gal; Activated UDP-Galactose derivative; Galactosyl donor reagent; Nucleotide-sugar analog
EINECS	Contact for details

Quality Control

Every batch of 2,4,6-Trinitrophenyl-Uridine Diphosphate Galactose is subjected to rigorous analytical testing to ensure identity, purity, and functional performance for research applications. We adhere to stringent in-house quality standards to guarantee batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to moisture, elevated temperature, or light may lead to decomposition. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90% (Functional activity)
Water Content (KF)	≤ 3.0%
Solubility	Soluble in DMSO, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.