Description

1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclobutyl-3-Methyl- (9Ci) is a specialized heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its highly reactive carbonyl chloride functional group, which enables efficient coupling reactions to construct complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its unique cyclobutyl-methyl substituted pyrazole scaffold makes it a valuable precursor for creating compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the pyrazole moiety's bioactivity.
• Ligand Synthesis for Catalysis: Serves as a precursor for creating specialized pyrazole-based ligands used in transition metal catalysis for fine chemical production.
• Material Science Precursor: Employed in the research and development of advanced organic materials, such as polymers or liquid crystals with specific electronic properties.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclobutyl-3-Methyl- (9Ci)
CAS No.	129506-39-4
Molecular Formula	C9H11ClN2O
Molecular Weight	198.65 g/mol
Synonyms	1-Cyclobutyl-3-methyl-1H-pyrazole-5-carbonyl chloride; 1-Cyclobutyl-3-methylpyrazole-5-carbonyl chloride; 1-Cyclobutyl-3-methyl-1H-pyrazole-5-carboxylic acid chloride; 1-Cyclobutyl-3-methyl-5-pyrazolecarbonyl chloride; 1-Cyclobutyl-3-methyl-1H-pyrazole-5-carboxyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-5-Carbonyl Chloride, 1-Cyclobutyl-3-Methyl- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. All materials are subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality management systems and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.