Description

6-Azido-n-Boc-Hexylamine is a bifunctional organic building block featuring both a protected amine and a reactive azide group. This compound is essential for advanced organic synthesis, particularly in click chemistry and bioconjugation strategies, enabling the efficient and selective formation of complex molecular architectures. It is a critical intermediate for researchers and manufacturers in pharmaceutical development, materials science, and chemical biology who require high-purity, reliable reagents for peptide modification, polymer functionalization, and probe synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC).
• Bioconjugation & Probe Development: Used for labeling biomolecules (proteins, antibodies, oligonucleotides) with fluorescent dyes, affinity tags, or other functional moieties.
• Polymer & Materials Science: Functional monomer for creating azide-terminated polymers, hydrogels, and surface coatings with "clickable" properties for further modification.
• Peptide Chemistry: Enables site-specific modification of peptides during solid-phase peptide synthesis (SPPS) by introducing the azido handle at the N-terminus or side chain.
• Chemical Biology Tool: Serves as a versatile linker or spacer arm in the development of chemical probes for studying biological pathways and protein interactions.
• Agrochemical Research: Intermediate in the synthesis of novel agrochemical compounds requiring specific amine-azide functionalities.

Basic Information

Product Name	6-Azido-n-Boc-Hexylamine
CAS No.	129392-87-6
Molecular Formula	C₁₁H₂₂N₄O₂
Molecular Weight	242.32 g/mol
Synonyms	1-Azido-6-[(tert-butoxycarbonyl)amino]hexane; N-(6-Azidohexyl)carbamic Acid tert-Butyl Ester; Boc-6-Azidohexylamine; 6-Azido-1-(Boc-amino)hexane; tert-Butyl N-(6-azidohexyl)carbamate; N-Boc-1,6-diaminohexane azide; Azido-PEG6-amine Boc-protected; (6-Azidohexyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 6-Azido-n-Boc-Hexylamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is moisture-sensitive and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.