Description

(5-Azidopentyl)Carbamic Acid tert-Butyl Ester is a specialized bifunctional organic compound featuring both a protected amine and a reactive azide group. This unique structure makes it a valuable building block in organic synthesis, particularly for click chemistry applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, bioconjugation, and materials science industries for the development of novel chemical entities and functionalized polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those requiring azide-alkyne cycloaddition (CuAAC) for conjugation.
• Bioconjugation Reagent: Used for site-specific labeling and modification of biomolecules such as proteins, peptides, and oligonucleotides via click chemistry.
• Polymer Functionalization: Serves as a monomer or cross-linking agent to introduce azide functionalities into polymer backbones for creating advanced materials with tailored properties.
• Chemical Probe Synthesis: Employed in medicinal chemistry and chemical biology to create probes for target identification, imaging, and diagnostic applications.
• Peptide Synthesis: Acts as a protected amino acid derivative for the solid-phase or solution-phase synthesis of modified peptides.
• Linker Chemistry: Useful in the construction of cleavable or non-cleavable linkers for antibody-drug conjugates (ADCs) and other targeted therapeutics.

Basic Information

Item	Detail
Product Name	(5-Azidopentyl)Carbamic Acid tert-Butyl Ester
CAS No.	129392-86-5
Molecular Formula	C10H20N4O2
Molecular Weight	228.29 g/mol
Synonyms	N-(5-Azidopentyl)-N-Boc-amine; tert-Butyl (5-azidopentyl)carbamate; Boc-NH-(CH2)5-N3; 5-Azido-1-(tert-butoxycarbonylamino)pentane; N-Boc-1,5-diaminopentane azide; 1-Azido-5-[(tert-butoxycarbonyl)amino]pentane; Boc-5-azidopentylamine
EINECS	Contact for details

Quality Control

Our (5-Azidopentyl)Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and structural integrity. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.