Description

tert-Butyl (4-Azidobutyl)Carbamate is a specialized bifunctional organic building block featuring both a protected amine (Boc) group and a reactive azide moiety. This compound is critical for advanced synthetic chemistry, enabling the controlled introduction of amine functionality via click chemistry or Staudinger ligation pathways. It is primarily utilized by researchers and process chemists in the pharmaceutical, bioconjugation, and materials science sectors for the synthesis of complex molecules, peptide mimetics, and functionalized polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly in medicinal chemistry programs.
• Peptide & Protein Modification: Used in bioconjugation strategies to label or cross-link biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating azide-functionalized polymers, hydrogels, and smart materials.
• Chemical Biology Probes: Enables the synthesis of activity-based probes and affinity tags for studying biological processes and target identification.
• Linker Chemistry: Employed in solid-phase peptide synthesis (SPPS) and combinatorial chemistry to construct diverse molecular libraries.
• Agrochemical Research: Intermediate in the development of novel crop protection agents and specialty agrochemicals.

Basic Information

Product Name	tert-Butyl (4-Azidobutyl)Carbamate
CAS No.	129392-85-4
Molecular Formula	C9H18N4O2
Molecular Weight	214.27 g/mol
Synonyms	Boc-4-azidobutylamine; 4-Azido-1-[(tert-butoxycarbonyl)amino]butane; 1-Boc-amino-4-azidobutane; N-Boc-1,4-diaminobutane azide; N-(tert-Butoxycarbonyl)-4-azidobutylamine; tert-Butyl N-(4-azidobutyl)carbamate; 4-Azidobutylcarbamic acid tert-butyl ester; N-Boc-4-azidobutylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (4-Azidobutyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and potentially shock-sensitive azide group, handle with appropriate precautions and avoid exposure to heat, strong acids, and heavy metals.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.