Description

tert-Butyl (3-Azidopropyl)Carbamate is a versatile bifunctional organic building block, primarily recognized for its azide and carbamate-protected amine functionalities. This compound is of significant value in advanced organic synthesis, particularly for the construction of complex molecules via click chemistry and other bioorthogonal reactions. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and bioconjugation sectors, enabling the efficient synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring triazole linkages formed via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Bioconjugation & Probe Development: Used to introduce azide handles onto biomolecules (proteins, peptides, antibodies) for subsequent labeling, imaging, or drug targeting applications.
• Polymer & Material Science: Serves as a monomer or functionalization agent for creating smart polymers, hydrogels, and surface coatings with tailored chemical properties.
• Agrochemical Synthesis: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Peptide Synthesis: Provides a protected amine group for solid-phase peptide synthesis (SPPS), allowing for sequential and controlled chain elongation.
• Chemical Biology Research: Enables the study of biological processes through the creation of activity-based probes and affinity labels.

Basic Information

Product Name	tert-Butyl (3-Azidopropyl)Carbamate
CAS No.	129392-84-3
Molecular Formula	C8H16N4O2
Molecular Weight	200.24 g/mol
Synonyms	Boc-3-azidopropylamine; 3-Azido-1-propylamine, N-Boc-protected; 1-Azido-3-[(tert-butoxycarbonyl)amino]propane; N-(3-Azidopropyl)carbamic acid tert-butyl ester; tert-Butyl N-(3-azidopropyl)carbamate; Boc-NH-(CH2)3-N3; N-Boc-3-azidopropylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl (3-Azidopropyl)Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and industrial applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive nature, containers should be kept in opaque or amber packaging. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.