Description

2'-Deoxywyosine is a chemically modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. Its unique structure makes it a valuable building block for probing nucleic acid interactions and designing novel therapeutic agents. This high-purity compound is essential for researchers and developers in the fields of antiviral drug discovery, oligonucleotide synthesis, and molecular biology, where precise chemical tools are required to study and manipulate genetic material.

Application

• Antiviral and Anticancer Nucleoside Analog Synthesis: Serves as a key intermediate in the research and development of novel therapeutic agents targeting viral replication and cancer cell proliferation.
• Oligonucleotide and Antisense Technology: Used as a modified building block in the synthesis of specialized oligonucleotides for gene silencing, diagnostic probes, and structural studies of RNA/DNA.
• Biochemical Research: Employed as a tool compound to study enzyme mechanisms, particularly those involving tRNA modification and nucleic acid processing enzymes.
• Medicinal Chemistry & Lead Optimization: Provides a scaffold for structure-activity relationship (SAR) studies to improve the potency and selectivity of nucleoside-based drugs.
• Academic and Institutional Research: Supports fundamental research in chemical biology, exploring the role of modified nucleosides in cellular function and disease.

Basic Information

Product Name	2'-Deoxywyosine
CAS No.	129266-21-3
Molecular Formula	C11H13N5O3
Molecular Weight	263.25 g/mol
Synonyms	2'-Deoxywyosine; 2-Amino-6-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purine-7,9-dione; 2'-Deoxywyosine nucleoside; 2-Amino-6-(2-deoxy-β-D-erythro-pentofuranosyl)-7,9-dihydropurine-7,9-dione; 2'-dWyosine; dWy; 2'-Deoxywybutosine (related analog); 2'-Deoxywybutoxosine (related analog)
EINECS	Contact for details

Quality Control

Our 2'-Deoxywyosine is manufactured under strict quality control protocols to ensure the high purity and consistency required for research applications. Each batch is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment to maintain product integrity and prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.