Description

5-Formyloxymethyluridine is a modified nucleoside derivative of uridine, featuring a formyloxymethyl group at the 5-position. This specific chemical modification is of significant interest in the field of nucleic acid chemistry and medicinal research, where it serves as a versatile building block and a key intermediate for the synthesis of more complex biomolecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in oligonucleotide synthesis, prodrug development, and the study of nucleoside metabolism. The compound, with CAS number 129051-71-4, is handled under controlled conditions to maintain its integrity for sensitive applications.

Application

• Oligonucleotide Synthesis: As a protected or modified monomer for the solid-phase synthesis of research oligonucleotides and antisense agents.
• Prodrug Development: Serving as a key intermediate in the design and synthesis of nucleoside prodrugs to enhance bioavailability and targeting.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and nucleic acid processing.
• Medicinal Chemistry: A valuable building block for creating novel nucleoside analogs with potential antiviral or anticancer activity.
• Diagnostic Reagent Manufacturing: Potential use in the development of labeled probes or components for diagnostic assays.

Basic Information

Product Name	5-Formyloxymethyluridine
CAS No.	129051-71-4
Molecular Formula	C11H14N2O8
Molecular Weight	302.24 g/mol
Synonyms	5-(Formyloxymethyl)uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-5-(hydroxymethyl)pyrimidine-2,4-dione formate; Uridine, 5-(formyloxymethyl)-; 5-Fomu; 5-Formyloxymethyl-Urd
EINECS	Contact for details

Quality Control

Our 5-Formyloxymethyluridine is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed batch-specific data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation. For long-term storage, consider conditions under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.