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10-Acetylsalicyldithranol CAS NO 128864-32-4


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CAS No.:128864-32-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

10-Acetylsalicyldithranol is a synthetic chemical intermediate of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key precursor in the synthesis of novel therapeutic agents, particularly those targeting dermatological and inflammatory conditions. Pharmaceutical manufacturers and R&D laboratories specializing in anti-psoriatic and anti-inflammatory drug discovery are the primary users of this high-purity intermediate.

Application

  • Pharmaceutical Intermediate: A critical building block in the synthesis of novel dithranol (anthralin) analogs and derivatives for dermatological treatments.
  • Anti-Psoriatic Agent Research: Used in the development and study of next-generation topical medications for psoriasis and other hyperproliferative skin disorders.
  • Anti-Inflammatory Drug Development: Serves as a precursor for compounds being investigated for their anti-inflammatory and immunomodulatory properties.
  • Academic & Institutional Research: Utilized in university and institutional labs for pharmacological studies and structure-activity relationship (SAR) research.
  • Process Chemistry: Acts as a key intermediate in scale-up and process optimization for the manufacture of active pharmaceutical ingredients (APIs).

Basic Information

Product Name 10-Acetylsalicyldithranol
CAS No. 128864-32-4
Molecular Formula C23H18O4
Molecular Weight 358.39 g/mol
Synonyms 10-Acetylsalicyldithranol; 1,8-Dihydroxy-10-[(2-hydroxyphenyl)acetyl]-9(10H)-anthracenone; 10-(2-Hydroxybenzoyl)dithranol; Acetylsalicyldithranol; Dithranol-10-acetylsalicylate; 10-Acetylsalicylanthralin
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Quality Control

Our 10-Acetylsalicyldithranol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring specific analytical data or regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item Specification
Appearance Yellow to orange-yellow powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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