Description

2,2,2-Trifluoro-1-(3-Methoxyphenyl) Ethanol is a high-value fluorinated aromatic alcohol building block. This compound is significant for its trifluoromethyl and methoxyphenyl groups, which are key motifs in modern pharmaceutical and agrochemical design. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystals used in advanced display technologies.
• Chiral Ligand/ Catalyst Preparation: Employed in the preparation of chiral auxiliaries and catalysts for asymmetric synthesis.
• Organic Electronic Materials: A potential monomer or dopant in the synthesis of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Fluorine-19 NMR Spectroscopy: Can be used as a reference compound or a probe in magnetic resonance studies.

Basic Information

Product Name	2,2,2-Trifluoro-1-(3-Methoxyphenyl) Ethanol
CAS No.	128816-77-3
Molecular Formula	C9H9F3O2
Molecular Weight	206.16 g/mol
Synonyms	1-(3-Methoxyphenyl)-2,2,2-trifluoroethanol; 3-Methoxy-α-(trifluoromethyl)benzyl alcohol; α-(Trifluoromethyl)-3-methoxybenzyl alcohol; 2,2,2-Trifluoro-1-(3-methoxyphenyl)ethan-1-ol; 3-Methoxy-α,α,α-trifluorotoluene alcohol; (3-Methoxyphenyl)(trifluoromethyl)methanol; 1-(3-Methoxyphenyl)-2,2,2-trifluoro-1-ethanol
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(3-Methoxyphenyl) Ethanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and chiral purity analysis, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with full traceability are provided for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.