Description

1H-Indole-3-Carbonyl Chloride, 7-Methoxy- (9Ci) is a versatile and reactive indole derivative, specifically an acid chloride, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the 7-methoxyindole-3-carbonyl moiety, a privileged scaffold in medicinal chemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate the indole structure.
• Biochemical Research: Serves as a derivatization agent or a building block for creating molecular probes, enzyme inhibitors, and receptor ligands for biological studies.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and advanced organic materials with unique optical or electronic properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Item	Details
Product Name	1H-Indole-3-Carbonyl Chloride, 7-Methoxy- (9Ci)
CAS No.	128717-78-2
Molecular Formula	C10H8ClNO2
Molecular Weight	209.63 g/mol
Synonyms	7-Methoxyindole-3-carbonyl chloride; 7-Methoxy-1H-indole-3-carbonyl chloride; 3-Carboxy-7-methoxyindole chloride; 7-Methoxy-1H-indole-3-carboxylic acid chloride; 7-Methoxyindole-3-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carbonyl Chloride, 7-Methoxy- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.