Description

Lychnostatin 2 (CAS NO 128700-84-5) is a specialized cyclic depsipeptide compound of significant interest in biochemical research and development. This molecule serves as a potent and selective inhibitor of phospholipase A2, a key enzyme involved in inflammatory pathways. It is primarily utilized by pharmaceutical researchers, medicinal chemists, and academic institutions engaged in the study of inflammation, signal transduction, and the development of novel therapeutic agents. Its unique mechanism of action makes it a critical tool for probing enzyme function and validating biological targets.

Application

• Biochemical Research: As a standard or reference compound in studies focusing on phospholipase A2 (PLA2) enzyme kinetics and inhibition mechanisms.
• Pharmaceutical R&D: A key pharmacological tool for target validation in drug discovery programs aimed at treating inflammatory diseases, such as arthritis and asthma.
• Cell Biology Studies: Used to modulate arachidonic acid release and eicosanoid production in cellular models to study inflammatory cascades.
• Academic Research: Employed in university and institutional labs for fundamental research into lipid metabolism and signal transduction pathways.
• Enzyme Profiling: Utilized in high-throughput screening (HTS) assays to identify and characterize new PLA2 inhibitors or to assess selectivity panels.

Basic Information

Product Name	Lychnostatin 2
CAS No.	128700-84-5
Molecular Formula	C54H85N7O15
Molecular Weight	1056.3 g/mol
Synonyms	Lychnostatine 2; Lychnostatin-2; (3S,6R,9S,12R,15S,18S,21S,24S,27S,30S,33S,36S,39S)-39-[[(2S)-2-Amino-3-phenylpropanoyl]amino]-33-(3-amino-3-oxopropyl)-6,15,24-tris(2-amino-2-oxoethyl)-9,18,27-tris(1H-indol-3-ylmethyl)-3,12,21,30-tetrakis(hydroxymethyl)-1,4,7,10,13,16,19,22,25,28,31,34,37-tridecaoxa-2,5,8,11,14,17,20,23,26,29,32,35,38-tridecazacyclotetratetracontane-36,40-dione; PLA2 Inhibitor Lychnostatin 2.
EINECS	Contact for details

Quality Control

Our Lychnostatin 2 is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Identification (IR)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.